Q: Is a social isolation a state of complete or near-complete lack of contact between an individual and society? ¶
A: Yes.
Q: Is a social isolation associated with gene expression — specifically? ¶
A: Yes, and the under-expression of genes bearing anti-inflammatory glucocorticoid response elements and over-expression of genes bearing response elements for pro-inflammatory NF-κB/Rel transcription factors.
Q: Is a social isolation not beneficial to an individual's mental health? ¶
A: Yes.
Q: Is a social isolation both a potential cause and a symptom of emotional or psychological challenges? ¶
A: Yes.